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Table 1 Top 30 orphan proteins for further study

From: Prioritizing orphan proteins for further study using phylogenomics and gene expression profiles in Streptomyces coelicolor

Gene Name Annotation Final rank Orphanicity rank Exp. quantile p-value act bac non-bac
SCO1521 hypothetical protein 1 1 0.21 3.71E-10 44 5 5
SCO2301 hypothetical protein 6 4 0.34 3.27E-07 43 5 5
SCO5362 hypothetical protein 6.5 9 0.13 2.02E-07 44 4 7
SCO1769 hypothetical protein 8 5 0.12 3.08E-08 40 3 1
SCO5746 hypothetical protein 8 7 0.18 4.38E-18 20 3 1
SCO3882 hypothetical protein 8.5 2 0.18 6.71E-08 38 5 1
SCO5546 hypothetical protein 8.5 14 0.35 7.62E-09 42 3 6
SCO5745 hypothetical protein 9.5 17 0.02 9.49E-10 43 4 6
SCO1925 hypothetical protein 11.5 18 0.09 1.24E-07 44 5 3
SCO2577 hypothetical protein 12 3 0.64 2.66E-07 41 5 1
SCO1676 hypothetical protein 12.5 15 0.32 7.05E-09 31 1 4
SCO1919 hypothetical protein 12.5 11 0.16 5.74E-07 44 4 2
SCO5491 hypothetical protein 12.5 6 0.35 3.07E-07 32 3 3
SCO2081 hypothetical protein 13 8 0.60 2.88E-08 38 2 1
SCO2902 hypothetical protein 14.5 22 0.37 3.05E-07 43 5 4
SCO1522 hypothetical protein 15.5 19 0.19 6.47E-07 43 3 5
SCO1920 hypothetical protein 16 12 0.27 1.71E-06 42 5 5
SCO3839 hypothetical protein 16.5 27 0.35 1.60E-08 35 3 2
SCO3960 hypothetical protein 17.5 13 0.30 5.66E-08 29 5 1
SCO2901 hypothetical protein 18 23 0.36 5.37E-07 41 3 5
SCO1924 hypothetical protein 18.5 20 0.08 6.81E-08 44 1 2
SCO6766 hypothetical protein 18.5 10 0.19 4.55E-08 20 1 2
SCO1775 hypothetical protein 21 16 0.32 3.00E-06 42 4 2
SCO1222 hypothetical protein 22 21 0.43 3.33E-09 27 1 1
SCO5645 hypothetical protein 22 28 0.07 3.11E-07 36 4 2
SCO1530 hypothetical protein 24.5 24 0.03 8.99E-07 43 1 5
SCO2497 hypothetical protein 26.5 29 0.52 2.38E-06 37 5 7
SCO5787 hypothetical protein 27 26 0.12 5.88E-06 44 3 7
SCO2599 hypothetical protein 27.5 25 0.13 4.17E-07 44 1 1
SCO5711 hypothetical protein 29.5 30 0.12 8.65E-06 44 5 5
  1. The proteins are prioritized according to their conservation across actinomycetes, bacteria and non-bacteria; their expression dynamics (summarized in the p-value); and their orphanicity, i.e. the absence of any functional information, assessed as described in the text.