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Table 3 Genes significantly up regulated exclusively in unstressed aak- 2 mutants relative to wild type and the GO terms (biological process) associated with them

From: Gene expression profiling of oxidative stress response of C. elegans aging defective AMPK mutants using massively parallel transcriptome sequencing

Function

Genes

Pvalue

GO as name

Reproduction

mtm-3, ptc-1, spd-5, puf-8, t21b10.3, egl-27, top-1, c23g10.8, npp-7, dab-1, prp-8, gld-3, smk-1, sur-6, mbk-2, atx-2, ptc-2, nmy-2, ruvb-1, pbrm-1, mep-1, zk858.1, mom-5, egl-45, c08b11.3, lin-35, scc-3, daz-1, f37c12.7, y71h2am.20, eif-3.b, csr-1, t09e8.1

2.14E-10

reproductive process,

 

daz-1, f37c12.7, puf-8, ptp-2, top-1, gld-3, y71h2am.20, smk-1, mbk-2, eif-3.b, nmy-2, csr-1, ruvb-1, tag-319, mep-1, zk858.1, t09e8.1

4.14E-04

gamete generation,

 

atx-2, ptc-2, mtm-3, ptc-1, egl-27, mom-5, egl-45, dab-1, lin-35, sur-6, smk-1

8.17E-04

oviposition,

 

atx-2, puf-8, gld-3

8.17E-04

feminization of hermaphroditic germ-line,

 

mep-1, ptp-2, let-92, lin-45, lin-35, sur-6

1.22E-02

vulval development,

 

puf-8, gld-3, scc-3

2.78E-02

regulation of meiosis,

 

egl-27, mom-5, lin-45, mbk-2

5.22E-02

cell fate commitment,

 

top-1, f17c11.10, smk-1, scc-3

6.15E-02

chromosome segregation,

 

npp-7, mbk-2, spd-5

8.21E-02

fertilization,

 

ptp-2, top-1, smk-1

9.86E-02

oogenesis,

 

top-1, smk-1

9.86E-02

oocyte development,

 

vit-1, vit-2, vit-3, vit-4, vit-5, vit-6

7.68E-03

lipid transport,

Cell cycle

let-92, nmy-2, mat-1, spd-5, egl-27, mom-5, lig-1, mbk-2, sur-6

2.69E-03

cell division,

 

atx-2, puf-8, mom-5, rpn-1, gld-3, scc-3, mbk-2

2.78E-02

cell cycle process,

 

mom-5, let-92, lig-1, sur-6, mat-1, mbk-2, spd-5

1.53E-02

embryonic cleavage, cytokinesis,

Anatomical structure development

let-92, t21b10.3, ptp-2, unc-76, prp-8, c23g10.8, top-1, sur-6, smk-1, nmy-2, lin-45, ruvb-1, pbrm-1, zk858.1, mep-1, c08b11.3, lin-35, scc-3

2.99E-04

organ development,

 

mtm-3, f37c12.7, t21b10.3, ptp-2, egl-27, ani-2, c23g10.8, top-1, smk-1, sur-6, lin-45, let-711, npl-4.1, zk858.1, mom-5, npl-4.2, c08b11.3, lin-35, scc-3, let-92, daf-18, unc-76, prp-8, pap-1, eif-3.b, mbk-2, nmy-2, ruvb-1, paa-1, pbrm-1, mep-1, ran-5

6.96E-10

anatomical structure development,

 

nmy-2, let-711, paa-1, npl-4.1, f37c12.7, t21b10.3, egl-27, npl-4.2, daf-18, top-1, lin-35, sur-6, mbk-2

1.18E-05

morphogenesis of an epithelium,

 

t14g10.5, nmy-2, pqn-51, spd-5, ran-5, mom-5, ptp-2, unc-76, daf-18, npp-7, dab-1, scc-3, eif-3.b, sur-6, mbk-2

7.10E-02

cellular component organization and biogenesis,

Response to stimulus

mtm-3, ptc-1, f37c12.7, t21b10.3, egl-27, ptp-2, dab-1, top-1, pap-1, smk-1, sur-6, eif-3.b, t12a2.2, t14g10.5, atx-2, ptc-2, let-711, pbrm-1, npl-4.1, arx-2, ran-5, mom-5, egl-45, npl-4.2, lin-35, scc-3

9.47E-05

locomotory behavior,

 

daf-16, mtm-3, ptc-1, cdc-14, f37c12.7, t21b10.3, ptp-2, egl-27, daf-18, top-1, dab-1, lig-1, pap-1, smk-1, sur-6, eif-3.b, t12a2.2, col-179, atx-2, t14g10.5, ptc-2, let-711, pbrm-1, npl-4.1, arx-2, ran-5, mom-5, npl-4.2, egl-45, lin-35, scc-3

2.55E-05

response to stimulus,

 

rpb-2, daf-16, let-711, daf-18, smk-1, eif-3.b

5.22E-02

determination of adult life span,

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BMC Research Notes

ISSN: 1756-0500

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