Table 2 HIV group: Clinical profile and aPL prevalence
ACS+: HIV+ | ACS-: HIV+ | p value | |
|---|---|---|---|
Demographic Profile: | |||
Black African n(%) | 30(100) | 30(100) | 1.0 |
Mean Age (years) | 43 ± 7 | 41 ± 8 | N/S |
Men (%) | 20(67) | 19(63) | N/S |
HIV related factors: | |||
CD4(cells/mm3) median(range) | 230 (30 -1356) | 125 (6-1041) | 0.013 |
Viral load (RNA copies/ml) median(range) | 29000 (25 - 7 × 105) | 54000(25-11 × 105) | N/S |
AIDS defining criteria n(%) | 11(37) | 21(70) | 0.01 |
Current oppurtunistic infection | 0 | 1(3) | N/S |
HIV related malignancies | 0 | 2(7) | N/S |
Coronary risk factors n(%): | |||
Smoking | 22(73) | 11(37) | 0.003 |
Diabetes Mellitus | 1(3) | 0(0) | N/S |
Hypertension | 7(23) | 2(7) | N/S |
Total cholesterol (mmol/l) | 3.6 ± 1.0 | 3.7+/-0.8 | N/S |
LDL cholesterol (mmol/l) | 2.2 ± 0.9 | 2.0 ± 0.5 | N/S |
HDL cholesterol (mmol/l) | 0.8 ± 0.3 | 1.0 ± 0.5 | 0.011 |
Triglycerides (mmol/l) | 1.4 ± 0.8 | 1.4+/-0.8 | N/S |
BMI (kg/m2) | 25 ± 5 | 21 ± 4 | 0.003 |
Other coronary risk factors | 2(7) | 0(0) | N/S |
Baseline aPL frequencies (%): | |||
Blood samples n(%) | 30(100) | 30(100) | 1.0 |
Anticardiolipin (IgG) | 14/30(47) | 17/30(57) | N/S |
Anticardiolipin (IgM) | 3/30(10) | 4/30(13) | N/S |
Anticardiolipin (IgA) | 0/30(0) | 0/30(0) | N/S |
Beta-2 Glycoprotein (IgG) | 11/30(37) | 10/30(33) | N/S |
Beta-2 Glycoprotein (IgM) | 3/30(10) | 2/30(7) | N/S |
Beta-2 Glycoprotein (IgA) | 7/30(23) | 8/30(27) | N/S |
Anti-Prothrombin (IgG) | 26/30(87) | 29/30(97) | N/S |
Anti-Prothrombin (IgM) | 2/30(7) | 0/30(0) | N/S |
Anti-Prothrombin (IgA) | 2/30(7) | 3/30(10) | N/S |