From: Comparisons of seven algorithms for pathway analysis using the WTCCC Crohn's Disease dataset
Algorithm | Software | Input | Null Hypothesis | Computer configuration | Runtime |
---|---|---|---|---|---|
GATES-Simes | KGG1 | Summary statistics | Self contained | Intel Core 2 Quad CPU Q9400 2.67 GHz, 4 GB RAM (desktop computer) | 30 mins5 |
GATES-Hyper | KGG | Summary statistics | Self contained | As above | 30 mins5 |
Aligator | R-SNPath2 | Summary statistics | Competitive | Intel XEON 2 six-core x5670 2.93 Ghz, 128 GB RAM (cluster) | 2 hours |
GRASS | R-SNPath | Raw data | Self contained | As above | 14 days |
GSEAforGWAS | GenGen3 | Raw data | Competitive | As above | 2 days |
PLINK-Ave | PLINK4 | Raw data | Self contained | As above | 40 hours |
PLINK-Max | PLINK | Raw data | Self contained | As above | 40 hours |