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Table 4 Running time summary

From: Comparisons of seven algorithms for pathway analysis using the WTCCC Crohn's Disease dataset

Algorithm

Software

Input

Null Hypothesis

Computer configuration

Runtime

GATES-Simes

KGG1

Summary statistics

Self contained

Intel Core 2 Quad CPU Q9400 2.67 GHz,

4 GB RAM (desktop computer)

30 mins5

GATES-Hyper

KGG

Summary statistics

Self contained

As above

30 mins5

Aligator

R-SNPath2

Summary statistics

Competitive

Intel XEON 2 six-core x5670 2.93 Ghz,

128 GB RAM (cluster)

2 hours

GRASS

R-SNPath

Raw data

Self contained

As above

14 days

GSEAforGWAS

GenGen3

Raw data

Competitive

As above

2 days

PLINK-Ave

PLINK4

Raw data

Self contained

As above

40 hours

PLINK-Max

PLINK

Raw data

Self contained

As above

40 hours

  1. Notes: 1, URL for KGG at http://bioinfo.hku.hk:13080/kggweb/home.htm; 2, URL for SNPath package at http://linchen.fhcrc.org/grass.html; 3, URL for GenGen program at http://www.openbioinformatics.org/gengen/; 4, URL for PLINK at http://pngu.mgh.harvard.edu/~purcell/plink/index.shtml; 5, excluding time spent building analysis genome (see KGG online manual).