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Figure 1 | BMC Research Notes

Figure 1

From: Identification of the calcitonin receptor in osteoarthritic chondrocytes

Figure 1

Allelic variants of CTR isoform 2 found in human chondrocytes. (A) A novel CALCR frameshift mutation was found in an OA patient. Electropherogram showing a heterozygous single nucleotide deletion at position +473 in CALCR cDNA amplified from primary chondrocytes. Note the appearance of a +1 frameshift in one of the alleles after nt +473. (B) Electropherograms showing the presence of CALCR single nucleotide polymorphisms in four different patients. Three C>T transitions were found at previously reported positions nt -6 (5'-UTR region) and +1340 (coding sequence), and unreported position nt +1443 (3'-UTR region). The complete sequences have been deposited at the INSDC nucleotide database (accession numbers FN994993 to FN994996).

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