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Table 1 Demographic and clinical characteristics of hematology patients with invasive fungal disease.

From: Prevalence of invasive fungal disease in hematological patients at a tertiary university hospital in Singapore

Median age, years (range)

43 (17 - 88)

Male gender (%)

25 (64.1)

Hematological diagnosis:

 

AML (% AML with IFD in study period)

12 (9.7)

ALL (% ALL with IFD in study period)

4 (3.8)

Autologous transplants (% autologous HSCT recipients with IFD)

1 (1.4)

Allogenic transplants (% allogeneic HSCT recipients with IFD)

10 (16.1)

   - Neutropenia post-transplantation (% allogeneic HSCT recipients with IFD occurring during neutropenia)

4 (6.5)

   - GVHD (% allogeneic HSCT recipients with IFD occurring during GVHD)

6 (9.7)

Relapsed leukemia on salvage chemotherapy post-transplantation

5

Others*

7

Location of IFD:

 

Sinus (%)

5 (12.8)

Pulmonary (%)

34 (87.2)

Median serum galactomannan (range) for:

 

   - All IFD cases (n = 41)

0.3 (0.1--4.3)

   - All probable/definite aspergillosis cases (n = 26)

0.6 (0.1--4.3)

  1. *Others include 2 cases with MDS, 2 cases with aplastic anemia, and one case each of chronic myelomonocytic leukemia, angioimmunoblastic T-cell lymphoma, and hemophagocytic lymphohistiocytosis secondary to T-cell lymphoma.