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Table 2 Antifungal activity of the Heliophila coronopifolia defensins

From: Four plant defensins from an indigenous South African Brassicaceae species display divergent activities against two test pathogens despite high sequence similarity in the encoding genes

  Botrytis cinerea Fusarium solani
Defensin IC50
µg ml-1
Hyphal morphology Spore lysis MPa IC50
µg ml-1
Hyphal morphology Spore lysis MPa
Hc-AFP1 > 25 Tip swelling No Yes > 25 Mild hyper-branching No No
Hc-AFP2 10-15 Severe hyper-branching
Tip swelling
Lysis
Yes Yes 10-15 Severe hyper-branching No Yes
Hc-AFP3 20-25 Severe hyper-branching
Tip swelling and disruption
Yes Yes > 25 Mild hyper-branching No No
Hc-AFP4 15-20 Mild hyper-branching
Tip swelling
No Yes 5-10 Severe hyper-branching No Yes
  1. aMP = Membrane permeabilization