Figure 2

Example analysis of cardiac hypertrophy using FUGA. A-D) Comparison of topological network properties in the gene co-expression network and 10 random networks generated using the Maslov-Sneppen rewiring model [16]. E) Cytoscape visualization of the gene co-expression network in cardiac hypertrophy. Each node represents a gene and links represent a co-expression. Node colors reflect gene cluster assignment (numerical labels) as determined by the Louvain algorithm and node sizes are proportional to node degrees. The largest 15 gene clusters are visualized. F) Enrichment of each network cluster for over-represented Gene Ontology Biological Process terms.