Table 2 hESC-associated signal pathways, TFs and miRNAs
From: Computational analysis of expression of human embryonic stem cell-associated signatures in tumors
Pathway | TF | miRNA |
|---|---|---|
Activin | TP53 | miR-143 |
AKT | MYC | miR-145 |
ALK | GATA4 | miR-187 |
ATM | SMAD1 | miR-296 |
BMI1 | ESRRB | miR-301 |
BMP | SOX2 | miR-21 |
Cell cycle | NANOG | let-7a |
EGF/EGFR | KLF4 | miR-371 |
ERBB2 | MYB | miR-372 |
ERK | MYCN | miR-373 |
FGF | ZFX | miR-367 |
Glycolysis | STAT3 | miR-302a |
Hippo | ZIC3 | miR-302a* |
IGF | ZFP42 | miR-302b |
JAK/STAT | SALL4 | miR-302b* |
c-KIT | REST | miR-302c |
Lefty | TCF3 | miR-302c* |
LIF | HOXB1 | miR-302d |
MAPK | HAND1 | miR-200c |
MEK/ERK | POU5F1 | miR-222 |
NF-κB | SRY |  |
NHEJ/HR a | TBX5 | Â |
Nodal | E2F4 | Â |
Notch | GATA6 | Â |
p53 | PAX6 | Â |
PRC2 | TCF4 | Â |
PDGF | FOXD3 | Â |
PI3K | CNOT3 | Â |
PTEN | ZEB2 | Â |
RAS | ESX1L | Â |
RTK | Â | Â |
Hedgehog (SHH) | Â | Â |
Smad | Â | Â |
Stat3 | Â | Â |
Telomerase | Â | Â |
TGFβ |  |  |
VEGF | Â | Â |
WNT | Â | Â |