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Table 2 hESC-associated signal pathways, TFs and miRNAs

From: Computational analysis of expression of human embryonic stem cell-associated signatures in tumors

Pathway TF miRNA
Activin TP53 miR-143
AKT MYC miR-145
ALK GATA4 miR-187
ATM SMAD1 miR-296
BMI1 ESRRB miR-301
BMP SOX2 miR-21
Cell cycle NANOG let-7a
EGF/EGFR KLF4 miR-371
ERBB2 MYB miR-372
ERK MYCN miR-373
FGF ZFX miR-367
Glycolysis STAT3 miR-302a
Hippo ZIC3 miR-302a*
IGF ZFP42 miR-302b
JAK/STAT SALL4 miR-302b*
c-KIT REST miR-302c
Lefty TCF3 miR-302c*
LIF HOXB1 miR-302d
MAPK HAND1 miR-200c
MEK/ERK POU5F1 miR-222
NF-κB SRY  
NHEJ/HR a TBX5  
Nodal E2F4  
Notch GATA6  
p53 PAX6  
PRC2 TCF4  
PDGF FOXD3  
PI3K CNOT3  
PTEN ZEB2  
RAS ESX1L  
RTK   
Hedgehog (SHH)   
Smad   
Stat3   
Telomerase   
TGFβ   
VEGF   
WNT   
  1. a NHEJ: non-homologous DNA end-joining; HR: homologous recombination