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Figure 3 | BMC Research Notes

Figure 3

From: Antiviral mode of action of bovine dialyzable leukocyte extract against human immunodeficiency virus type 1 infection

Figure 3

Inhibition of Env/CD4-mediated membrane fusion. β-gal activity was measured after CD4 cells and Env cells were co-cultured after exposure to A) bDLE, B) UC781 and C) T-20 under different circumstances: (■) CD4 cells were exposed to the compound and co-cultured with Env cells for 24 hours; (▲) CD4 cells were exposed to the compound for 30 minutes, washed, and co-cultured with Env cells for 24 hours; (✘) Env cells were exposed to the compound for 30 minutes, washed, and co-cultured with CD4 cells for 24 hours. Percentage values are relative to the positive control (cell-to-cell fusion without pretreatment with drug). The data represent the means ± standard deviations from three separate experiments, each of which was carried out in duplicate.

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