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Figure 3 | BMC Research Notes

Figure 3

From: Integration of gene expression data with prior knowledge for network analysis and validation

Figure 3

Comparison of the reference and filtered networks' disconnectivity. A vertex' value indicates the portion of all connected pairs of vertices in the network that become disconnected after its removal. For better comparison, the values are normalized to fill the interval [0, 1]. (A) The scaled Dis in the breast cancer data strictly filtered network is plotted against the scaled Dis in the underlying reference network. EGF pathway-related kinases increase while p53 drastically decrease. (B) In the corresponding 1-extended network, a large cluster of nodes has small Dis before and after filtering, only p53 remains at the highest level.

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