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Table 1 Clinical characteristics of Finnish pre-eclampsia (PE) patients and control subjects (mean and standard deviation SD) combined from Finnish population based Data set (Data set 1), Southern Finland PE Data set (Data set 2) and Eastern Finland PE Data Set (Data set 3)

From: Association of the rs1424954 polymorphism of the ACVR2A gene with the risk of pre-eclampsia is not replicated in a Finnish study population

  Pre-eclampsia Controls   
  Primiparous (n = 321) Multiparous (n = 164) Primiparous (n = 264) Multiparous (n = 185) Primiparous Multiparous
  N Mean SD N Mean SD N Mean SD N Mean SD p * p *
Age (years) 321 27.7 5.4 164 31.8 5.2 264 27.6 4.7 185 31.0 4.9 0.374 0.177
BMI (kg/m2) 302 23.8 4.5 162 24.6 4.4 264 22.2 3.1 185 23.2 3.7 < 0.001 0.002
Systolic BP (mmHg) 315 167.0 18.4 154 169.6 17.1 80 118.6 9.0 22 119.1 11.9 < 0.001 < 0.001
Diastolic BP (mmHg) 316 105.7 10.1 154 105.1 10.4 80 73.6 7.8 22 72.2 8.9 < 0.001 < 0.001
Birth weight (g) 320 2399.9 934.6 162 2382.6 863.2 264 3537.8 404.0 185 3635.0 412.8 < 0.001 < 0.001
Relative birth weight (SD) 311 -1.4 1.3 160 -1.2 1.3 262 -0.2 0.8 183 0.0 0.8 < 0.001 < 0.001
Gestational age at birth (weeks) 315 35.7 3.9 164 35.5 3.5 264 39.9 1.5 185 40.0 1.2 < 0.001 < 0.001
  N %   N %   N %   N %   p** p**
Gestational diabetes 16 5.4   7 4.3   5 1.9   12 6.5   0.046 0.362
Pre-gestational diabetes 8 2.7   5 3.1   1 0,0   1 0.5   0.046 0.103
  1. * Student's t-test or Mann-Whitney test. ** Chi-square test or Fisher's exact test