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Table 1 Clinical characteristics of Finnish pre-eclampsia (PE) patients and control subjects (mean and standard deviation SD) combined from Finnish population based Data set (Data set 1), Southern Finland PE Data set (Data set 2) and Eastern Finland PE Data Set (Data set 3)

From: Association of the rs1424954 polymorphism of the ACVR2A gene with the risk of pre-eclampsia is not replicated in a Finnish study population

 

Pre-eclampsia

Controls

  
 

Primiparous (n = 321)

Multiparous (n = 164)

Primiparous (n = 264)

Multiparous (n = 185)

Primiparous

Multiparous

 

N

Mean

SD

N

Mean

SD

N

Mean

SD

N

Mean

SD

p *

p *

Age (years)

321

27.7

5.4

164

31.8

5.2

264

27.6

4.7

185

31.0

4.9

0.374

0.177

BMI (kg/m2)

302

23.8

4.5

162

24.6

4.4

264

22.2

3.1

185

23.2

3.7

< 0.001

0.002

Systolic BP (mmHg)

315

167.0

18.4

154

169.6

17.1

80

118.6

9.0

22

119.1

11.9

< 0.001

< 0.001

Diastolic BP (mmHg)

316

105.7

10.1

154

105.1

10.4

80

73.6

7.8

22

72.2

8.9

< 0.001

< 0.001

Birth weight (g)

320

2399.9

934.6

162

2382.6

863.2

264

3537.8

404.0

185

3635.0

412.8

< 0.001

< 0.001

Relative birth weight (SD)

311

-1.4

1.3

160

-1.2

1.3

262

-0.2

0.8

183

0.0

0.8

< 0.001

< 0.001

Gestational age at birth (weeks)

315

35.7

3.9

164

35.5

3.5

264

39.9

1.5

185

40.0

1.2

< 0.001

< 0.001

 

N

%

 

N

%

 

N

%

 

N

%

 

p**

p**

Gestational diabetes

16

5.4

 

7

4.3

 

5

1.9

 

12

6.5

 

0.046

0.362

Pre-gestational diabetes

8

2.7

 

5

3.1

 

1

0,0

 

1

0.5

 

0.046

0.103

  1. * Student's t-test or Mann-Whitney test. ** Chi-square test or Fisher's exact test