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Table 2 ACVR2A genotypes and allele counts among Finnish pre-eclampsia (PE) patients and control subjects combined from Finnish population based Data set (Data set 1), Southern Finland PE Data set (Data set 2) and Eastern Finland PE Data Set (Data set 3)

From: Association of the rs1424954 polymorphism of the ACVR2A gene with the risk of pre-eclampsia is not replicated in a Finnish study population

 

Pre-eclampsia

Controls

p**

 

Primiparous (n = 321)

Multiparous (n = 164)

Combined (n = 485)

Primiparous (n = 264)

Multiparous (n = 185)

Combined (n = 449)

Primiparous

Multiparous

Combined

Genotypes

GG

134

67

201

108

87

195

   

AG

148

70

218

121

76

197

   

AA

32

24

56

33

21

54

0.468

0.660

0.871

N/A*

7

3

10

2

1

3

   

Alleles (Frequency)

G

416

204

620

337

250

587

   

A

212

118

330

187

118

305

0.493

0.205

0.806

  1. * Genotyping failed ** Chi-square test