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Table 1 Baseline profiles and HBV/HIV viral load profile of 21 chronic HBV carriers on HAART

From: Emergence of HBV resistance to lamivudine (3TC) in HIV/HBV co-infected patients in The Gambia, West Africa

Baseline time point

Treatment

Patient ID

Age

Sex

HBeAg

ALT/AST

HIV type

CD4

Treatment duration (Months)

HIV VL

Pre HAART

HIV VL

end point

HBV VL

Pre HAART

HBV VL

end point

 

(yrs)

  

(IU/ml)

 

Count (/mm3)

 

(c/mL)

 

(c/mL

 

1

42

M

-

33/28

HIV-1

110

25

1.0 × 106

1.0 × 102

6.5 × 104

4.5 × 104

3

37

F

-

32/23

HIV-1

10

25

8.7 × 105

1.0 × 102

2.8 × 104

< 260

5

40

M

-

37/33

HIV-1

990

44

4.7 × 102

1.0 × 102

5.9 x105

2.4 × 108

6

35

F

+

95/39

HIV-1 & 2

300

33

3.6 × 104 (HIV-1) < 1.0 × 102 (HIV-2

1.0 × 102

(HIV-1 & HIV-2)

1.0 × 106

3.7 × 107

7

28

F

+

67/43

HIV-1

290

22

7.3 × 104

1.0 × 102

3.5 × 107

1.4 × 103

9

44

M

+

83/25

HIV-1

240

6

2.3 × 108

1.0 × 102

5.4 × 108

1.8 × 109

10

40

M

+

99/5

HIV-1

80

25

1.0 × 106

1.2 × 104

2.3 × 108

6.5 × 103

12

48

M

-

38/21

HIV-1

80

26

1.0 × 106

2.0 × 104

3.0 × 107

7.9 × 107

13

36

M

-

54/22

HIV-1

60

36

4.1 × 105

1.0 × 102

4.6 × 107

2.5 × 107

16

41

F

-

42/12

HIV-2

340

25

1.3 x106

1.0 × 102

1.2 × 108

< 260

17

27

M

-

NT

HIV-1

10

12

7.5 × 104

1.0 × 102

5.0 × 105

< 260

18

50

F

+

NT

HIV-1

210

18

1.8 × 105

1.0 × 102

7.9 × 108

8.1 × 104

19

24

F

+

40/22

HIV-1

160

50

1.6 × 105

1.0 × 102

1.5 × 109

< 260

21

42

F

-

35/24

HIV-2

650

24

1.5 × 104

1.0 × 102

1.7 × 104

< 260

22

29

F

-

42/21

HIV-1

160

24

1.0 × 106

1.0 × 102

1.1 × 109

4.5 × 104

23

52

M

-

38/23

HIV-1

50

50

5.6 × 104

1.0 × 102

5.9 × 103

< 260

24

29

F

-

29/12

HIV-1

220

52

2.4 × 105

1.0 × 102

< 260

< 260

25

31

F

-

27/11

HIV-1

10

36

1.0 × 102

1.0 × 102

1.0 × 104

< 260

26

50

M

-

32/19

HIV-1

130

30

3.0 × 105

1.0 × 102

9.2 × 103

< 260

28

39

F

-

21/4

HIV-1

360

19

4.2 × 103

1.4 × 103

2. 8 × 104

< 260

29

30

F

-

553/397

HIV-1

220

36

5.1 × 105

1.0 × 102

5.7 × 108

< 260

  1. The upper normal limit of ALT and AST liver enzyme levels is 46 international units/ml (IU/mL; NT-samples were not tested for AST and ALT.
  2. The lower limit of detection of real-time PCR was 260 copies/mL (c/mL) and 100 copies/mL for HBV and HIV respectively.