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Table 2 Genotype and allele frequencies of the C1772T and the G1790A polymorphisms of the HIF1A gene in PE patients and the control group

From: Polymorphisms in the hypoxia-inducible factor 1 alpha gene in Mexican patients with preeclampsia: A case-control study

Nucleotide Amino acids Genotypes PE (%) Control (%) P-value OR (95% CI)
C1772T Pro582 CC 137 (91.3) 95 (90.5)   
  Ser582 CT 13 (8.7) 10 (9.5)   
   TT 0 (0.0) 0 (0.0)   
   CT + TT 13 (8.7) 10 (9.5) 0.203 * 0.485 (0.178-1.067)
   Allele     
   C 287 (95.7) 200 (95.2) 0.831 0.906 (0.389-2.107)
   T 13 (4.3) 10 (4.8)   
   Genotypes     
G1790A Ala588 GG 150 (100.0) 104 (99.3)   
  Thr588 GA 0 (0.0) 1 (0.7)   
   AA 0 (0.0) 0 (0.0)   
   GA + AA 0 (0.0) 1 (0.7) 0.412 ** 0.232 (0.009-5.737)
   Allele     
   G 300 (100.0) 209 (99.5) 0.411 0.232 (0.009-5.737)
   A 0 (0.0) 1 (0.5)   
  1. PE, preeclampsia; OR, odds ratio; CI, confidence intervals. * Calculations were performed CC vs. CT + TT. ** Calculations were performed GG vs. GA + AA