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Figure 5 | BMC Research Notes

Figure 5

From: Comprehensive behavioral analysis of ENU-induced Disc1-Q31L and -L100P mutant mice

Figure 5

Depression-like behavior and sensorimotor gating. (A, B) Porsolt forced swim test: (A) immobility time (sec) on day 1 and day 2 in 31 L mutant and control mice and (B) in 100P mutant and control mice were recorded. On day 1, 100P mutants showed a significantly higher immobility time. (C, D) Tail suspension test: (C) immobility time (sec) in 31 L mutant and control mice and also (D) immobility time (sec) in 100P mutant and control mice were recorded. No significant differences in immobility time were found between the genotypes in each strain. (E, F) Startle response/prepulse inhibition test: (E) amplitudes of the startle response and (F) percentage of prepulse inhibition were recorded; there were no significant genotype effects on the behavioral indices in each strain. Data represent the mean ± SEM. The p values indicate a genotype effect in a t-test (A-D) or a two-way repeated measures ANOVA (E, F).

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