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Table 2 Quantitative Real Time PCR in HeLa S3 cells after treating with increasing concentrations of different molecules.

From: Bisquinolinium compounds induce quadruplex-specific transcriptome changes in HeLa S3 cell lines

 

CTPS2

DPY30

DIO2

EGFR

CANX

AK1

PFKM

SH3GL1

TGOLN2

8979A-10 uM

1.18

(▬)

-1.23

(▬)

1.13

(▬)

-1.79

(▬)

-1.45

(▬)

2.02

(▬)

-1.99

(▬)

1.61

(▬)

-1.29

(▬)

8979A-100 uM

1.28

(▬)

1.00

(▬)

-1.37

(▬)

1.95

(▬)

1.14

(▬)

-1.91

(▬)

1.06

(▬)

1.95

(▬)

1.82

(▬)

PhenDC3-10 uM

3.06

(▲)

-1.79

()

1.35

(▲)

-1.39

()

12.69

(▲)

-1.61

()

  

1.06

(▬)

PhenDC3-20 uM

2.09

(▲)

-1.83

()

1.41

(▲)

-1.65

()

10.78

(▲)

-1.41

()

   

PhenDC3-50 uM

1.93

(▲)

-3.59

()

1.99

(▲)

-1.78

()

7.06 (▲)

-1.59

()

   

PhenDC3-100 uM

1.50

(▲)

-3.60

()

2.19

(▲)

-1.99

()

6.42

(▲)

-1.76

()

  

1.04

(▬)

360A-10 uM

3.01

(▲)

-2.06

()

-1.24

()

2.41

(▲)

  

1.86

(▲)

1.29

(▲)

1.43

(▬)

360A-20 uM

1.65

(▲)

-1.11

()

-1.08

()

2.42

(▲)

  

4.13

(▲)

3.73

(▲)

 

360A-50 uM

3.73

(▲)

-1.89

()

-1.69

()

6.23

(▲)

  

1.87

(▲)

1.25

(▲)

 

360A-100 uM

8.22

(▲)

-1.22

()

-2.17

()

13.11

(▲)

  

2.23

(▲)

2.34

(▲)

-1.12

(▬)

  1. The status in microarray is shown in parenthesis as unchanged (▬), upregulated (▲) or downregulated ()