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Table 3 Gene Ontology (GO) categories enriched/depleted (P < 0.01) of differentially expressed genes after treating HeLa S3 cells with PhenDC3

From: Bisquinolinium compounds induce quadruplex-specific transcriptome changes in HeLa S3 cell lines

GO ID

TERM

P VALUE

Enriched GO classes

  

GO:0044237

cellular metabolic process

2.42E-12

GO:0034960

cellular biopolymer metabolic process

5.07E-12

GO:0044260

cellular macromolecule metabolic process

2.90E-11

GO:0043283

biopolymer metabolic process

5.91E-11

GO:0008152

metabolic process

1.19E-10

GO:0043170

macromolecule metabolic process

2.94E-10

GO:0044238

primary metabolic process

8.10E-10

GO:0006139

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

1.91E-07

GO:0010467

gene expression

2.15E-07

GO:0009987

cellular process

4.16E-07

GO:0043284

biopolymer biosynthetic process

1.28E-06

GO:0034961

cellular biopolymer biosynthetic process

1.28E-06

GO:0016070

RNA metabolic process

1.90E-06

GO:0034645

cellular macromolecule biosynthetic process

5.34E-06

GO:0009059

macromolecule biosynthetic process

8.73E-06

GO:0046907

intracellular transport

0.0001430

GO:0051641

cellular localization

0.0002268

GO:0006357

regulation of transcription from RNA polymerase II promoter

0.0003508

GO:0044249

cellular biosynthetic process

0.0007565

GO:0009058

biosynthetic process

0.0009248

GO:0051649

establishment of localization in cell

0.0013971

GO:0044267

cellular protein metabolic process

0.0075149

Depleted GO classes

  

GO:0002376

immune system process

0.0074009

GO:0007186

G-protein coupled receptor protein signaling pathway

0.0063202

GO:0007166

cell surface receptor linked signal transduction

0.0002492

GO:0006955

immune response

0.0001782

GO:0032501

multicellular organismal process

4.93E-06