Table 1 Associations between SNPs in TLRs and gB-Specific Antibody Responses After 3 doses of CMV vaccine
Gene | SNP | Location | Minor Allele | Counts* | β | Standard Error | P value | Median ELISA** |
|---|---|---|---|---|---|---|---|---|
TLR7 | rs179009 | intron | C | 4/47/91 | 0.386 | 0.116 | 0.001 | 21102/13194/9769 |
TLR7 | rs179008 | coding | T | 4/34/104 | 0.304 | 0.128 | 0.019 | 21102/12907/10340 |
TLR7 | rs179018 | intron | G | 4/36/102 | 0.318 | 0.130 | 0.016 | 16610/12907/10691 |
TLR7 | rs179013 | intron | T | 3/34/105 | 0.315 | 0.136 | 0.022 | 22940/13501/10530 |
IKBKE | rs1953090 | intron | C | 15/62/64 | -0.275 | 0.097 | 0.005 | 10904/9676/14993 |
TLR3 | rs3775292 | intron | G | 5/40/96 | 0.296 | 0.117 | 0.012 | 10904/13685/9662 |
IRAK4 | rs1838341 | intron | G | 0/16/126 | -0.458 | 0.204 | 0.027 | NA/6394/11378 |
TLR9 | rs5743849 | intron | T | 0/16/126 | -0.469 | 0.211 | 0.028 | NA/6635/11424 |