Table 2 Infant anthropometry at baseline, 2 and 4 weeks, and 3 months for randomised groups and the breast-fed reference group (results are mean(SD))
From: Infant feeding bottle design, growth and behaviour: results from a randomised trial
| Â | Avent | Dr Brown | Difference (95% CI) | p | Breast-fed |
|---|---|---|---|---|---|
| Â | n = 31 | n = 32 | n = 74 | Â | Â |
Birth weight (g) | 3518 (441) | 3322 (381) | 196 (-15 - 407) | 0.07 | 3363 (407) |
Birthweight SDS | 0.15 (0.92) | -0.24 (0.78) | 0.39 (-0.05 - 0.83) | 0.08 | -0.13 (0.90) |
Enrolment | Â | Â | Â | Â | Â |
Age at randomisation or enrolment (days) | 7.5 (3.7) | 7.1 (3.1) | Â | Â | 7.5 (2.1) |
Weight (g) | 3559 (537) | 3340 (375) | 219 (-16.8 - 454) | 0.07 | 3352 (393) |
Weight SD | -0.40 (0.93) | -0.73 (0.74) | 0.33 (-0.1 - 0.76) | 0.1 | -0.71 (0.86) |
Length (cm) | 51.1 (2.6) | 50.3 (2.0) | 0.81 (-0.35 - 2.0) | 0.2 | 50.5 (2.5) |
Length SD | -0.33 (1.15) | -0.62 (0.99) | 0.29 (-0.25 - 0.83) | 0.3 | -0.53 (1.28) |
OFC (cm) | 35.8 (1.5) | 35.1 (1.5) | 0.73 (-0.02 - 1.5) | 0.06 | 35.4 (1.4) |
OFC SD | 0.22 (1.07) | -0.28 (1.1) | 0.50 (-0.04 - 1.04) | 0.07 | -0.07 (1.2) |
2 weeks | n = 24 | n = 20 | Â | Â | n = 66 |
Age (days) | 14.8 (1.7) | 15.2 (2.6) | 14.7 (2.1) | Â | Â |
Weight (g) | 3776 (509) | 3575 (311) | 201 (-62 - 465) | 0.1 | 3635 (385) |
Weight SD | -0.35 (0.91) | -0.53 (0.76) | 0.18 (-0.34 - 0.69) | 0.5 | -0.56 (0.80) |
Length (cm) | 52.3 (2.3) | 51.2 (1.9) | 1.14 (-0.18 - 2.5) | 0.09 | 52.3 (2.4) |
Length SD | -0.13 (1.08) | -0.58 (0.90) | 0.39 (-0.23 - 1.0) | 0.2 | -0.06 (1.23) |
OFC (cm) | 36.5 (1.4) | 35.8 (0.95) | 0.72 (-0.024 - 1.5) | 0.06 | 36.2 (1.0) |
OFC SD | 0.31 (1.0) | -0.20 (0.76) | 0.44 (-0.11 - 0.99) | 0.1 | 0.12 (0.89) |
4 weeks | n = 27 | n = 22 | Â | Â | n = 65 |
Age (days) | 29.0 (2.3) | 29.8 (3.6) | Â | Â | 29.1 (2.9) |
Weight (g) | 4294 (503) | 4181 (380) | 151 (-111 - 414) | 0.3 | 4244 (451) |
Weight SD | 0.33 (1.28) | -0.27 (0.73) | 0.6 (0.016 - 1.19) | 0.04 | -0.14 (0.87) |
Length (cm) | 54.0 (2.2) | 53.4 (2.0) | 0.71 (-0.5 - 1.9) | 0.2 | 54.4 (2.0) |
Length SD | 0.27 (1.24) | -0.33 (1.01) | 0.6 (-0.04 - 1.2) | 0.07 | 0.16 (0.99) |
OFC (cm) | 37.6 (1.28) | 37.4 (0.9) | 0.32 (-0.31 - 0.9) | 0.3 | 37.6 (1.5) |
OFC SD | 0.80 (1.34) | 0.32 (1.1) | 0.48 (-0.24 - 1.2) | 0.2 | 0.22 (0.84) |
3 months | n = 26 | n = 23 | Â | Â | n = 61 |
Age (yrs) | 0.25 (0.04) | 0.24 (0.03) | Â | Â | 0.25 (0.02) |
Weight (kg) | 6.30 (0.78) | 6.00 (0.68) | 0.31 (-0.11 - 0.73) | 0.1 | 6.04 (0.70) |
Weight SDS | 0.36 (1.0) | 0.09 (0.94) | 0.26 (-0.29 - 0.82) | 0.3 | 0.04 (1.07) |
Length (cm) | 60.9 (2.2) | 59.9 (2.0) | 0.96 (-0.24 - 2.2) | 0.1 | 60.9 (2.7) |
Length SDS | 0.25 (1.0) | -0.07 (1.0) | 0.33 (-0.23 - 0.88) | 0.2 | 0.27 (1.3) |
OFC (cm) | 41.0 (1.6) | 40.5 (1.2) | 0.54 (-0.29 - 1.4) | 0.2 | 40.5 (1.1) |
OFC SDS | 0.16 (1.1) | -0.11 (0.9) | 0.27 (-0.32 - 0.86) | 0.4 | -0.25 (1.0) |