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Table 2 Comparison of Atopobium vaginae isolates and Bacteroides fragilis type strain MIC-values (μg/ml) for clindamycin and metronidazole

From: Susceptibility testing of Atopobium vaginae for dequalinium chloride

 

Atopobium vaginae CCUG 44258

Atopobium vaginae CCUG 44125

Atopobium vaginae

CCUG 38953T

Bacteroides fragilis

ATCC 25285T

Metronidazole [this study]a

32

128

32

1

Metronidazole [15]b

4

8

16

1

Metronidazole [10]a

NT

NT

> 32

NT

Clindamycin [this study]a

< 0.0625

< 0.0625

< 0.0625

< 0.0625

Clindamycin [8]c

< 0.016

< 0.016

< 0.016

NT

Clindamycin [16]a, *

NT

NT

NT

≤ 0.25 - > 16

  1. MIC: Minimal Inhibitory Concentration; NT: Not tested
  2. a: CLSI broth microdilution, b: Agar dilution method, c: E-test
  3. * Range based on the MICs of 232 clinical isolates of B. fragilis (the type strain was not included)