Figure 2

Accumulation MR lesion maps depending on the rs11833579 (A) or rs12425791 (B) genotype. Quantitative maps of diffusion/fluid attenuation inversion recovery (FLAIR)/T2/gradient-echo (GE) MR images show no significant difference between the age-sex matched patients with the rs11833579 A/A or G/A genotype and those with the G/G genotype (A). In the age-sex matched patients with the rs12425791 A/A or G/A genotype (B), compared with the ones with the G/G genotype, the extent of leukoaraiosis in the centrum semiovale (first row) and corona radiata (second row) on FLAIR MRIs appears to be smaller. The pseudocolor bars indicate numbers of subjects with lesions overlapping a specific pixel.