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Table 1 Anti-correlated and positively correlated mRNA/microRNA pairs in the tumour and/or the normal samples

From: Identifying microRNA/mRNA dysregulations in ovarian cancer

microRNA mRNA normal tumour MicroRNA Regulation in tumour vs. normal Gene Regulation in tumour vs. normal P-value
hsa-miR-140-3p RAD51AP1 - - Down Up 0.002
hsa-miR-96 KIF23 none - Up Up 0.006
hsa-miR-96 BIRC5 none - Up Up 0.003
hsa-miR-140-3p RACGAP1 none - Down Up 0.012
hsa-miR-139-5p RACGAP1 none - Down Up 0.012
hsa-miR-133a GCLC none - Down Down 0.023
hsa-miR-16 E2F3 none - Up Up 0.027
hsa-miR-140-3p C8ORF30A none - Down Up 0.022
hsa-miR-15b C8ORF30A none - Up Up 0.011
hsa-miR-16 C8ORF30A none - Up Up 0.001
hsa-miR-16 SCAMP5 none - Up Up 3.7E-4
hsa-miR-18a DNAI1 none - Up Down 0.038
hsa-miR-18b DNAI1 none - Up Down 0.014
hsa-miR-590-5p E2F3 + - Up Up 0.020
hsa-miR-34c-5p E2F3 + - Down Up 0.028
hsa-miR-16 CDC25C + + Up Up 0.016
hsa-miR-18a GINS1 + + Up Up 0.0
hsa-miR-18b GINS1 + + Up Up 0.0
hsa-miR-18a RAD51AP1 none + Up Up 6.1E-06
hsa-miR-18b RAD51AP1 none + Up Up 6.2E-07
hsa-miR-15b RACGAP1 none + Up Up 0.009
  1. a) This Table lists the 21 mRNA/microRNA regulatory pairs found in ovarian tumour samples. The microRNA shown are also differentially expressed in tumour samples compared with normal, exhibit seed sequence complementarity in the gene shown, and are significantly anti-correlated (red) or positively correlated (blue) with the corresponding mRNA in the tumour samples. The third and fourth columns show the type of correlation (if present) within normal and tumour samples respectively. A "+" symbol represents a positive correlation, while "-" represents an anti-correlation, and "none" represents no significant correlation across the samples