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Table 1 Medians and central 95% distribution of concentrations of steroids (ng/mL) in blood of apathetic children at the entry in the study and at the last follow-up

From: Patterns of endogenous steroids in apathetic refugee children are compatible with long-term stress

  Baseline Last follow-up Chi-square, p-value
Illness Score 29.5 (22–35) 0 (0–1) 15.61 (<0.001)
Cortisol 101 (19–154) 103 (85–137) 0.081 (0.776)
Cortisone 25 (13–32) 28 (21–31) 3.12 (0.077)
Total Glucocorticoids 142 (32–201) 128 (91–170) 0.029 (0.870)
25 hydroxy vitamin D 10 (5–22) 12 (6–23) 0.925 (0.336)
Estrone    
Girls 0.039 (0.012–0.19) 0.08 (0.01–0.087) 1.37 (0.242)
Boys 0.018 (0.003–0.039) 0.023 (0.005–0.024) 0.083 (0.773)
Estradiol    
Girls 0.05 (0.01–0.26) 0.12 (0.008–0.17) 0.771 (0.380)
Boys 0.01 (0.01–0.041) 0.018 (0.006–0.024) 0.333 (0.564)
DHEA    
Girls 5.0 (1.9–8.8) 4.2 (2.1–5.4) 0.343 (0.558)
Boys 2.6 (1.6–5.6) 3.3 (1.2–6.1) 0.083 (0.773)
Androstenedione    
Girls 1.2 (0.6–2.4) 1.2 (0.6–1.6) 0.342 (0.545)
Boys 0.6 (0.2–1.1) 0.6 (0.2–1.3) 0.00 (1.00)
Testosterone    
Girls 0.29 (0.2–0.5) 0.26 (0.15–0.39) 0.263 (0.608)
Boys 4.5 (0.1–7.0) 4.3 (0.04–5.9) 0.0833 (0.773)
Dihydrotestosterone    
Girls 0.084 (0.003–0.088) 0.05 (0.03–0.066) 1.05 (0.307)
Boys 0.18 (0.03–2.24) 0.22 (0.015–0.29) 0.333 (0.563)
Pregnenolone 1.73 (0.55–3.78) 1.32 (0.7–2.62) 0.989 (0.319)
17OH-Pregnenolone 2.1 (0.5–5.8) 2.3 (1.0–4.5) 0.990 (0.319)
Allopregnenolone 0.07 (0.02–0.3) 0.07 (0.02–1.4) 0.005 (0.943)
Progesterone    
Girls 0.28 (0.04–3.6) 0.39 (0.03–9.8) 0.021 (0.883)
Boys 0.11 (0.05–0.12) 0.07 (0.06–0.15) 0.0854 (0.770)
17OH-Progesterone    
Girls 0.33 (0.21–1.0) 0.42 (0.22–0.85) 0.0215 (0.884)
Boys 0.64 (0.27–1.0) 0.52 (0.28–0.77) 0.333 (0.564)
11Deoxycortisol 0.5 (0.1–1.4) 0.6 (0.2–1.3) 0.021 (0.887)
Deoxycorticosterone 0.7 (0.5–2) 0.7 (0.3–1.5) 0.612 (0.434)
Corticosterone 4.9 (0.3–15.2) 3.8 (1.7–13.1) 0.00 (1.00)
  1. Girls: n = 7, mean age 14.2; boys: n = 4, mean age 14.8.