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Table 2 Serum levels of vitamin D and bone biomarkers before and after vitamin D supplementation

From: Effects of vitamin D supplementation on the bone specific biomarkers in HIV infected individuals under treatment with efavirenz

Parameter Baseline (pre-intervention) Three months later (post-intervention) P value
Serum 25-OH vitamin D (nmol/L) 18.54 ± 12.92 96.10 ± 37.05 <0.001
PTH (pg/ml) 33.92 ± 17.96 22.53 ± 18.69 <0.001
Serum ALP (IU/L) 200.80 ± 72.05 273.52 ± 96.55 <0.001
Serum Osteocalcin (ng/ml) 3.60 ± 3.76 11.09 ± 7.32 <0.001*
Serum CTx (ng/ml) 0.48 ± 0.25 0.77 ± 0.40 <0.001
  1. ALP: Alkaline Phosphatase; CTx:Collagen Type 1 C-Telopeptide; PTH: Parathyroid Hormone.
  2. * Sign test was used to evaluate the difference between pre and post intervention values.