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Table 3 The ILP changes upon reaching the PD 20 endpoint in 36 patients, stratified by the coefficient of repeatability of the various lung function parameters

From: The relationship between inspiratory lung function parameters and airway hyper-responsiveness in subjects with mild to moderate COPD

response criterion non-responder/responder (at PD20 endpoint FEV1)
FEV1 response >12%* 0 vs. 36 (0% vs. 100%)
FIV1 response >14%* 10 vs. 26 (28% vs. 72%)
IC response > 19%* 14 vs. 22 (39% vs. 61%)
FIF50 response >21%* 28 vs. 8 (78% vs. 22%)
PIF response >18%* 24 vs. 12 (67% vs. 33%)
  1. Definition of abbreviations:
  2. * = one-hour coefficient of repeatability of the particular lung function parameter
  3. FEV1 = forced expiratory volume in 1 second
  4. FIV1 = forced inspiratory volume in 1 second
  5. IC = inspiratory capacity (L)
  6. FIF50 = forced inspiratory flow at 50% of the vital capacity (L/s)
  7. PIF = peak inspiratory flow (L/s)