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Table 4 The mean percentage changes from the initial FEV 1 and ILP values in 36 subjects after inhaling histamine at the endpoint dose step (FEV 1 decrease ≥20%)

From: The relationship between inspiratory lung function parameters and airway hyper-responsiveness in subjects with mild to moderate COPD

 

mean percentage changes from initial values ± SD

correlation (rS) with changes in FEV1

FEV1

-24.9 ± 3.7 (n.t.)

-

FIV1

-20.1 ± 9.3 (p < 0.001)

0.47(p = 0.004)

IC

-20.6 ± 12.5 (p < 0.001)

0.22 (p = 0.206)

FIF50

-12.6 ± 11.1 (p < 0.001)

0.17 (p = 0.322)

PIF

-14.6 ± 11.2 (p < 0.001)

0.24 (p = 0.161)

  1. Definition of abbreviations:
  2. FEV1 = forced expiratory volume (L) in 1 second
  3. FIV1 = forced inspiratory volume (L) in 1 second
  4. IC = inspiratory capacity (L)
  5. FIF50 = forced inspiratory flow at 50% of the vital capacity (L/s)
  6. PIF = peak inspiratory flow (L/s)
  7. n.t. = not tested (less than -20% by design)
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BMC Research Notes

ISSN: 1756-0500

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