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Table 4 The mean percentage changes from the initial FEV 1 and ILP values in 36 subjects after inhaling histamine at the endpoint dose step (FEV 1 decrease ≥20%)

From: The relationship between inspiratory lung function parameters and airway hyper-responsiveness in subjects with mild to moderate COPD

  mean percentage changes from initial values ± SD correlation (rS) with changes in FEV1
FEV1 -24.9 ± 3.7 (n.t.) -
FIV1 -20.1 ± 9.3 (p < 0.001) 0.47(p = 0.004)
IC -20.6 ± 12.5 (p < 0.001) 0.22 (p = 0.206)
FIF50 -12.6 ± 11.1 (p < 0.001) 0.17 (p = 0.322)
PIF -14.6 ± 11.2 (p < 0.001) 0.24 (p = 0.161)
  1. Definition of abbreviations:
  2. FEV1 = forced expiratory volume (L) in 1 second
  3. FIV1 = forced inspiratory volume (L) in 1 second
  4. IC = inspiratory capacity (L)
  5. FIF50 = forced inspiratory flow at 50% of the vital capacity (L/s)
  6. PIF = peak inspiratory flow (L/s)
  7. n.t. = not tested (less than -20% by design)