Skip to main content

Table 2 Significant differences in mRNA expression between kidney cortex and the RCC types

From: Gene expression pattern of the epidermal growth factor receptor family and LRIG1 in renal cell carcinoma

  All RCC combined* ccRCC* pRCC* chRCC* Altered expression Difference RCC types†
EGFR < 0.001 0.001 0.016 NS Up-regulation NS
ErbB2 0.003 0.001 NS NS Down-regulation < 0.001
ErbB3 NS NS NS NS - NS
ErbB4 0.001 < 0.001 0.001 0.03 Down-regulation NS
LRIG1 NS 0.015 NS NS Down-regulation 0.002
  1. * P-values were calculated in comparison to kidney cortex using the Mann–Whitney U-test.
  2. † Comparison of the significant differences between the RCC types was performed using the Kruskal-Wallis test.
  3. NS, non-significant.