Gene expression pattern of the epidermal growth factor receptor family and LRIG1 in renal cell carcinoma

BMC Research Notes

Table 2 Significant differences in mRNA expression between kidney cortex and the RCC types

	All RCC combined*	ccRCC*	pRCC*	chRCC*	Altered expression	Difference RCC types†
EGFR	< 0.001	0.001	0.016	NS	Up-regulation	NS
ErbB2	0.003	0.001	NS	NS	Down-regulation	< 0.001
ErbB3	NS	NS	NS	NS	-	NS
ErbB4	0.001	< 0.001	0.001	0.03	Down-regulation	NS
LRIG1	NS	0.015	NS	NS	Down-regulation	0.002

* P-values were calculated in comparison to kidney cortex using the Mann–Whitney U-test.
† Comparison of the significant differences between the RCC types was performed using the Kruskal-Wallis test.
NS, non-significant.

ISSN: 1756-0500