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Table 1 Co-activity between CTFPs

From: Functional and topological characterization of transcriptional cooperativity in yeast

Condition

Average co-activity

Co-activity increase (in n -fold)

 p -value

Anearobic N-C-P-S chemostats

0.58

1.63

8.99*10-3

C-S-P-N chemostat limitation

0.49

1.25

4.73*10-2

Calcineurin

0.55

2.48

9.13*10-7

Carbon-limited chemostats

0.56

1.37

6.97*10-3

Cell Cycle

0.43

6.39

2.99*10-9

Cold shift

0.53

1.20

3.66*10-2

Compounds and stress

0.39

3.51

9.17*10-9

DNA damage

0.41

2.69

9.50*10-7

Environmental stress

0.42

3.64

9.38*10-9

Lithium response

0.56

1.29

2.34*10-1

Map kinase

0.34

2.12

1.62*10-4

Proteasome inhibitor

0.38

3.61

1.29*10-8

Regulation by PDR1

0.27

1.72

2.32*10-1

Rosetta compendium

0.37

4.24

2.09*10-9

Sporulation

0.27

1.60

1.91*10-2

TCA cycle mutants

0.28

2.46

5.41*10-6

Titratable promoter alleles

0.41

4.41

3.57*10-9

  1. Average co-activity (calculated using a squared Spearman's correlation coefficient) between members of the same CTFP. Increase in co-activity is calculated as the ratio of average correlation in CTFPs vs average correlation in 1000 non-cooperative TF pairs.