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Table 3 Breast cancer genes differentially expressed between CAW and AAW patient populations

From: Differential expression of breast cancer-associated genes between stage- and age-matched tumor specimens from African- and Caucasian-American Women diagnosed with breast cancer

Gene Description CAWa AAWb CAW/AAWc P-valued
 Genes Associated with Breast Cancer Prognosis 
AR Androgen receptor 0.99 0.38 2.60 0.002
BCL2 B-cell CLL/lymphoma 2 0.65 0.20 3.28 0.010
CCND1 Cyclin D1 0.78 0.28 2.75 0.030
CDKN1A Cyclin-dependent kinase inhibitor 1A 2.07 0.90 2.29 0.002
CDKN1B Cyclin-dependent kinase inhibitor 1B 1.68 0.74 2.26 0.001
CDKN2A Cyclin-dependent kinase inhibitor 2A 1.35 3.55 0.38 0.046
ERBB2 V-erb-b2 erythroblastic leukemia viral oncogene homolog 2 1.61 0.63 2.56 0.012
ESR1 Estrogen receptor 1 1.79 0.46 3.91 0.023
GATA3 GATA binding protein 3 1.57 0.17 9.33 0.001
IGFBP2 Insulin-like growth factor binding protein 2, 36 kDa 1.53 0.73 2.11 0.005
IL6ST Interleukin 6 signal transducer 1.15 0.44 2.64 0.005
KRT19 Keratin 19 1.44 0.71 2.03 0.012
MUC1 Mucin 1, cell surface associated 1.77 0.36 4.94 0.004
PGR Progesterone receptor 0.77 0.33 2.34 0.012
SERPINE1 Serpin peptidase inhibitor, clade E, member 1 7.59 3.18 2.38 0.014
 Genes Associated with Response to Chemotherapy 
HSPB1 Heat shock 27 kDa protein 1 0.98 0.46 2.14 0.003
SERPINA3 Serpin peptidase inhibitor, clade A, member 3 0.43 0.20 2.16 0.017
STC2 Stanniocalcin 2 0.79 0.38 2.05 0.019
 Genes Associated with Breast Cancer Progression 
CLDN7 Claudin 7 1.76 0.66 2.67 0.006
DLC1 Deleted in liver cancer 1 4.27 0.94 4.52 0.023
  1. a Average Gene Expression of Caucasion-American Women (CAW, n = 12).
  2. b Average Gene Expression of African-Amercian Women (AAW, n = 12).
  3. c Gene Expression Fold Change Relative to the Average Gene Expression of AAW.
  4. d P-values calculated using the Wilcoxin Rank Sum Test.