Figure 2
Effect of 17-AAG on HSP90 biomarkers in MMTV-NEU-NT tumours : Western blots are shown for NEU/HER2, C-RAF, heat shock protein HSP72 and CDK4 expression in MMTV-NEU-NT tumours following treatment in mice with vehicle control (lanes 1-3), and 17-AAG, 40mg/kg, days 1-3 (lanes 4-6). Tumours were excised 24 hours after the last dose. GAPDH was used as a loading control.