Variable | Losartan (n = 12) | Placebo (n = 14) |
---|---|---|
Age (y) | 66.5 (56–73) | 57.5 (38.5–63)a |
Gender (F: M) | 4: 8 | 6: 8 |
eGFR | 9.5 (6–16) | 12 (10–14.5) |
Hemoglobin | 111.5 (104–128.5) | 117 (111–138) |
Creatinine | 465 (322.5–597.3) | 440 (339–480) |
sSBP (mmHg) | 1142 (132–160) | 137 (130–153.5) |
sDBP (mmHg) | 74 (72–80) | 78 (70–86) |
sHR (bpm) | 64 (60–74) | 68 (61–74) |
Weight (kg) | 74.2 (71.4–88.3) | 80 (70–89.4) |
BSA (kg/m2) | 1.90 (1.76–2.10) | 1.91 (1.79–2.06) |
BNP (ng/L) | 285 (65–1194) | 163 (63–303.3) |
Additional antihypertensive medications (n) (non protocol) | 2.0 (0.5–2.5) | 2.0 (0–3) |