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Table 2 Results at baseline and 1 month in both the Losartan and Placebo groups

From: Can losartan and blood pressure control peri arteriovenous fistula creation ameliorate the early associated left ventricular hypertrophic response a randomised placebo controlled trial

Variable Losartan (A) baseline Losartan (B) 1 month Placebo (A) baseline Placebo (B) 1 month P
sSBP (mmHg) 142 (132–160) 129 (117–149)a 137 (130–153.5) 138 (127–141.5) A ns B ns
sDBP (mmHg) 74 (72–80) 70 (64–84) 78 (70–86) 79 (70–85.5) A ns B ns
sHR (bpm) 64 (60–74) 62 (56–80) 68 (61–74) 72 (66–78) A ns B ns
BNP 285 (65–1194) 325 (206–1798.5) 163 (63–303.3) 214 (144–277.5) A ns B ns
LVM (gm) 199.1 (148.5–225.2) 218.4 (146.5–262.2)a 182.7 (143.5–205.0) 173.8 (151.1–204.9) A ns B ns
LVMI (gm/m2) 99.6 (72.8–114.3) 83.5 (69.8–112) 91.3 (77.6–106.8) 92.7 (78.4–107.5) A ns B ns
RWT 0.40 (0.32–0.45) 0.36 (0.32–0.41) 0.40 (0.34–0.47) 0.37 (0.35–0.42) A ns B ns
CO (L/min) 5.3 (4.5–5.6) 5.9 (4.5–7.3) 4.4 (3.7–5.9) 5.3 (4.6–6.9) A ns B ns
E/E’ 15.0 (10.0–21.0) 12 (8.8–17.3) 11.4 (9.8–14.0) 10.4 (8.8–13.2)a A ns B ns
LAV (mLs) 66.5 (54.8–75.6) 74.3 (59.8–80.5) 65.0 (50.1–82.2) 65.1 (59.4–81.3) A ns B ns
EF (%) 55 (47–57.8) 52.5 (49.3–56.8) 52.5 (47.8–58.8) 52 (51–60) A ns B ns
  1. This table shows the sitting systolic (SBP) and diastolic (DBP) blood pressure and heart rate (HR), brain natriuretic peptide (BNP), left ventricular mass (LVM) and LVM index (LVMI), relative wall thickness (RWT), cardiac output (CO), E/E’, left atrial volume (LAV) and ejection fraction (EF) in the atenolol plus losartan (losartan) and atenolol plus placebo (placebo) groups at baseline (A) and 1 month (B). Data was compared utilising non-parametric tests: between groups (Mann–Whitney U) in the column labelled P (next to A for comparisons at baseline and next to B for comparisons at 1 month) and within groups (Wilcoxon), (from baseline to 1 month) when statistical significance was denoted by the letter a (a) if P <0.05 compared to baseline. (P denotes a two-tailed p value).