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Table 1 The Mayo classification of macroscopic venous invasion in renal cell carcinoma

From: Tumor thrombus of inferior vena cava in patients with renal cell carcinoma – clinical and oncological outcome of 50 patients after surgery

Level I Tumor thrombus is either at the entry of renal vein or within the IVC < 2 cm from the confluence of renal vein and IVC.
Level II Tumor thrombus extends within the IVC > 2 cm above the confluence of renal vein and IVC, but still remains below the hepatic veins.
Level III Tumor Thrombus involves the intrahepatic IVC.
Level IV Tumor thrombus extends above diaphragm or into the right atrium.