Figure 6From: Ribozyme-mediated gene knock down strategy to dissect the consequences of PDGF stimulation in vascular smooth muscle cellsWorking model describing the different effects on PDI-A3 and HSP-60 phosphorylation due to PDGFR-β knock-down. Ribozyme might impair the β-β and α-β dimer formations decreasing the opportunities of PDGF-BB binding. This inhibition might reduce (if not abolish) the PDGFR-β signaling pathway and conversely increase the PDGFR-α pathwayBack to article page