Study | Study areas | Age of population | Study group |
---|---|---|---|
Phase 3 RCT study | Â | Â | Â |
Efficacy study | 6 study municipalities | Children aged 6 weeks to 6 months and monitored until 2 years old | RCT |
Nested study | 3 predefined health centres included Dao (Tagbilaran), Danao and main health centre in Panglao | Children aged 6 weeks to 6 months and monitored until 2 years old | RCT |
Hospitalization in BRH | 6 study municipalities | Children less than 5 years old | RCT, EPI and Epi grey |
Hospitalization in the private hospital and OPD consultation in BRH | 6 study municipalities | Children less than 2 years old | RCT, EPI and Epi grey |
Satellite studies | Â | Â | Â |
Herd immunity | 6 study municipalities | Children enrolled in the efficacy study w/elder sibling enrolled in the efficacy study | RCT |
Cost effectiveness(hospitalization for pneumonia, sepsis, or meningitis at BRH and three private hospitals) | 6 study municipalities | Children enrolled in the efficacy study from 6 weeks to 23 months old and admitted to hospital or consulted the OPD | RCT |
Acute otitis media(hospitalization or consultation at BRH for pneumonia, sepsis, or meningitis) | 6 study municipalities | Children less than 5 years old diagnosed with pneumonia and/or AOM | RCT, EPI and Epi grey |
Wheezing(hospitalization or consultation at BRH for pneumonia, sepsis, or meningitis) | 6 study municipalities | Children less than 5 years old | RCT, EPI and Epi grey |
Pertussis(hospitalization or consultation at BRH for pneumonia, sepsis, or meningitis) | 6 study municipalities | Children less than 13 years old | RCT, EPI and Epi grey, children not necessary enrolled in RCT |