BowStrap v1.0: Assigning statistical significance to expressed genes using short-read transcriptome data

BMC Research Notes

Table 2 Spearman’s correlation between calculated gene expression and known gene model expression

Dataset	Random	Unique	BowStrap
50 M	0.91	0.80	1.00
25 M	0.90	0.80	1.00
10 M	0.90	0.81	0.99
1 M	0.89	0.81	0.96
0.5 M	0.87	0.81	0.94

Spearman’s Rank Correlation was calculated between gene model expression values in synthetic read data and ‘Bowtie’-based methods for estimation of gene model expression levels. Three ‘Bowtie’-based methods for gene model expression were considered, using gene model expression values from synthetic RNAseq data of 50, 25, 10, 1, and 0.5 million total 46-mer sequence reads.

ISSN: 1756-0500