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Table 2 Comparison of the in vitro activities of selected antimicrobial agents tested against Klebsiella spp. a (329 strains)

From: Resistance trends in gram-negative bacteria: surveillance results from two Mexican hospitals, 2005–2010

Antimicrobial agent MIC50 MIC90 Range % susceptible/resistantb
 Cefuroxime 4 >16 ≤2 – >16 62.3 / 32.2
 Cefoxitin ≤4 >16 ≤4 – >16 82.6 / 11.8
 Ceftriaxone ≤0.25 32 ≤0.25 – >32 63.8 / 35.2
 Ceftazidime ≤1 >16 ≤1 – >16 66.8 / 33.1
 Cefepime ≤0.12 8 ≤0.12 – >16 92.7 / 4.5
 Piperacillin/tazobactam  2 >64 ≤0.5 – >64 79.3 / 11.2
 Imipenem 0.25 0.5 ≤0.12 – >8 98.4 / 1.2
 Meropenem ≤0.12 0.25 ≤0.12 – >8 98.4 / 0.9
 Ciprofloxacin ≤0.03 >4 ≤0.03 – >4 80.8 / 18.2
 Levofloxacin ≤0.5 >4 ≤0.5 – >4 82.3 / 15.8
 Gentamicin ≤2 >8 ≤2 – >8 82.6 / 14.5
 Amikacin 2 >32 ≤4 – >32 84.1 / 13.1
 PolymyxinB  ≤0.5 ≤0.5 ≤0.5 – >4 99.2 / 0.6
 Colistin ≤0.5 ≤0.5 ≤0.5 – >4 99.5 / 0.4
  1. a Includes: Klebsiellaoxytoca (36 strains) Klebsiellapneumoniae (291 strains), Klebsiellaornithinolytica (1 strain) and unspeciated Klebsiella (1 strain).
  2. b Criteria as published by the CLSI [16].
  3. cPseudomonas aeruginosa breakpoints.