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Table 3 Minimal inhibitory concentration (MIC) of the studied plants extracts and chloramphenicol on the studied bacterial species

From: Antibacterial and antibiotic-potentiation activities of the methanol extract of some cameroonian spices against Gram-negative multi-drug resistant phenotypes

Bacterial strains

Tested samples and MIC in μg/ml in the absence and presence of PAßN (in parenthesis)

 

Aframomum citratum

Aframomum melegueta

Imperata cylindricum

Cinnamomum zeylanicum

Dorstenia psilurus

Fagara leprieuri

Monodora myristica

Pentadiplandra brazzeana

Piper guineense

Scorodophloeus zenkeri

Tetrapleura tetraptera

CHL

E. coli

            

ATCC8739

512

512

512

64

-

512

1024

1024

1024

1024

1024

1

ATCC10536

1024

512

1024

512

128

256

1024

512

1024

512

1024 (1024)

32 (<2)

AG100

1024 (1024)

1024 (1024)

1024 (256)

- (64)

- (1024)

1024 (1024)

512

1024 (1024)

1024 (512)

1024 (1024)

1024 (1024)

4 (<2)

AG100A

512 (128)

1024 (1024)

1024 (128)

512 (128)

512 (128)

512 (512)

1024 (1024)

- (−)

1024 (1024)

1024 (1024)

1024 (1024)

<2 (<2)

AG100ATET

512 (512)

1024 (1024)

1024 (1024)

512 (512)

512 (128)

1024 (1024)

-

-

1024

512

1024

32 (<2)

AG102

1024

-

1024

1024

512

1024

-

-

-

-

-

16 (<2)

MC4100

512 (512)

512 (256)

1024 (1024)

1024 (1024)

512 (256)

512

- (−)

1024 (1024)

1024 (1024)

1024 (1024)

512 (512)

4 (<2)

W3110

512 (256)

512 (512)

512 (512)

512 (512)

512 (256)

256

512

1024 (1024)

1024 (128)

512

512 (512)

1 (<2)

E. aerogenes

            

ATCC13048

1024

-

1024

1024

1024

1024

1024

-

-

-

-

8 (<2)

CM64

1024 (1024)

1024 (1024)

512 (128)

1024 (512)

512 (256)

1024 (1024)

1024 (1024)

1024 (1024)

1024 (1024)

1024 (1024)

512 (512)

32

EA27

512 (512)

1024 (1024)

512 (512)

512 (512)

- (−)

1024 (1024)

1024 (1024)

1024 (1024)

-(−)

1024 (1024)

1024 (512)

64 (32)

EA289

-

1024

-

1024

-

-

1024

1024

-

-

1024

256

EA298

1024

512

-

-

1024

-

256

256

512

256

1024

256

EA3

-

-

-

-

-

1024

-

-

-

-

-

256

E. cloacae

            

BM47

512 (512)

1024 (1024)

1024 (1024)

1024 (512)

1024 (128)

1024 (1024)

1024 (1024)

1024

1024

1024

1024

- (8)

BM67

512 (512)

1024 (1024)

1024 (1024)

1024 (1024)

1024 (128)

- (−)

- (−)

- (−)

- (−)

- (−)

- (−)

- (32)

ECCI69

512 (512)

1024 (1024)

1024 (1024)

1024 (1024)

-(−)

-(−)

1024 (1024)

- (−)

1024 (1024)

1024 (1024)

1024 (512)

- (32)

K. pneumoniae

            

ATCC12296

1024

1024

1024

1024

1024

1024

512

-

-

-

1024

4

K2

1024

-

1024

1024

1024

-

1024

-

-

-

-

-

K24

1024

1024

1024

1024

1024

1024

512

-

-

1024

1024

32 (<2)

KP55

512

1024

256

512

512

1024

1024

-

-

-

1024

32(<2)

KP63

512 (512)

1024 (1024)

1024 (1024)

512 (512)

512 (128)

1024 (512)

1024 (1024)

512

1024 (1024)

1024 (512)

1024 (1024)

64(<2)

P. stuartuii

            

ATCC29916

1024 (1024)

- (−)

-(−)

-(−)

1024 (1024)

-(−)

-(−)

-(−)

1024 (1024)

1024 (1024)

1024 (1024)

8

NEA16

1024 (512)

- (−)

1024 (1024)

512 (512)

512 (256)

1024

1024

-

-

1024

-

64(<2)

PS2636

1024

-

-

-

-

-

-

-

-

-

-

-

PS299645

512

512

1024

1024

1024

1024

-

1024

1024

512

1024

128

P. aeruginosa

            

PA01

-

-

-

-

-

-

-

-

-

-

-

-

PA124

-

-

-

-

-

-

-

-

-

1024

-

32(<2)

  1. (−): MIC not detected at up to 1024 μg/ml for the les extracts and 256 μg/ml for chloramphenicol. () : values in parenthesis are MIC of substance in the presence of PAßN at 20 μg/ml. The MIC of PAßN was 64 μg/ml on E. coli. AG100A. 512 μg/ml on ATCC11296. BM67. EA27. EA289; 1024 μg/ml on AG100ATET. ATCC13048. CM64; and > 1024 μg/ml on other bacteria. CHL: chloramphénicol; (in bold): significant MIC value.