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Table 5 Minimal inhibitory concentration (MIC) of antibiotics in absence and presence of Cinnamomum zeylanicum extract (μg/mL)

From: Antibacterial and antibiotic-potentiation activities of the methanol extract of some cameroonian spices against Gram-negative multi-drug resistant phenotypes

Bacterial strains

Antibiotics and MIC in absence and presence ofCinnamomum zeylanicum extract

Ampicillin

Cefepime

Chloramphenicol

Ciprofloxacin

Cloxacillin

Alone

MIC/2.5

MIC/5

Alone

MIC/2

MIC/5

Alone

MIC/2.5

MIC/5

Alone

MIC/2.5

MIC/5

Alone

MIC/2.5

MIC/5

AG100Atet

-

-

-

-

-

-

256

16 (16) S

32 (8) S

256

64 (4) S

128 (2) S

-

-

-

AG102

-

-

-

128

256 (0.5) I

256 (1) I

16

8 (2) S

16 (1) I

<2

<2

<2

-

256 (>1)S

-

CM64

-

256 (>1) S

-

-

256 (>1) S

-

nt

nt

nt

nt

nt

nt

-

-

-

KP63

-

32 (>8) S

-

256

32 (8) S

256 (1) I

-

32 (>8) S

256 (>1) S

64

128 (0.5) I

128(0.5)I

-

64 (>4)S

256 (>1)S

PA124

128

16 (8) S

64 (2) S

128

128 (1) I

128 (1) I

32

2 (16) S

8 (4) S

16

8 (2) S

16 (1) I

-

-

-

Bacterial strains

Erythromycin

Kanamycin

Norfloxacin

Streptomycin

Tetracycline

Alone

MIC/2.5

MIC/5

Alone

MIC/2.5

MIC/5

Alone

MIC/2.5

MIC/5

Alone

MIC/2.5

MIC/5

Alone

MIC/2.5

MIC/5

AG100Atet

64

16 (4) S

32 (2) S

-

16 (>16)S

128 (>2)S

128

128 (1) I

128 (1) I

<2

<2

<2

2

2 (1) I

2 (1) I

AG102

32

16 (2) S

16 (2) S

<2

<2

<2

<2

<2

<2

-

256 (>1) S

256 (>1)S

<2

<2

<2

CM64

-

128 (>2)S

256 (>1)S

4

<2 (>2) S

<2 (>2) S

4

<2 (>2) S

4 (1) I

32

4 (8) S

8 (4) S

nt

nt

nt

KP63

16

1 (16) S

4 (4) S

32

32 (1) I

32 (1) I

-

128 (>2)S

256 (>1)S

<4

<4

<4

<2

<2

<2

PA124

128

16 (8) S

32 (4) S

128

8 (16) S

32 (4) S

64

32 (2) S

64 (1) I

nt

nt

nt

8

2 (4) S

2 (4) S

  1. MIC/2.5: concentration of plant extract added equal to 204.8 μg/mL for AG100ATET. KP63; and to 409.6 μg/ml for PA124. CM64. AG102.
  2. MIC/5: concentration of plant extract added equal to 102. 4 μg/mL for AG100ATET. KP63; and to 204.8 μg/ml for PA124. CM64. AG102.
  3. (): Folds decreasing of MIC. S: synergy. I: indifference. nt: not tested; (−): MIC > 256 μg/ml.