Skip to main content

Table 6 Minimal inhibitory concentration (MIC) of antibiotics in absence and presence extracts Dorstenia psilurus (μg/ml)

From: Antibacterial and antibiotic-potentiation activities of the methanol extract of some cameroonian spices against Gram-negative multi-drug resistant phenotypes

Bacterial strains

Antibiotics and MIC in absence and presence ofDorstenia psilurus extract

Ampicillin

Cefepime

Chloramphenicol

Ciprofloxacin

Cloxacillin

Alone

MIC/2.5

MIC/5

Alone

MIC/2

MIC/5

Alone

MIC/2.5

MIC/5

Alone

MIC/2.5

MIC/5

Alone

MIC/2.5

MIC/5

AG100Atet

-

-

-

-

-

-

256

128 (2) S

256 (1) I

256

64 (4) S

128 (2) S

-

-

-

AG102

-

-

-

128

256 (0.5) I

256 (0.5) I

16

4 (4) S

4 (4) S

<2

<2

<2

-

-

-

CM64

-

256 (>1)S

-

-

64 (>4) S

64 (>4) S

nt

nt

nt

nt

nt

nt

-

256 (>1) S

-

KP63

-

32 (>8) S

-

256

64 (4) S

128 (2) S

-

64 (>4) S

256 (>1) S

64

64 (1) I

64 (1) I

-

64 (>4) S

256 (>1) S

PA124

128

64 (2) S

64 (2) S

128

128 (1) I

128 (1) I

32

16 (2) S

32 (1) I

16

16 (1) I

16 (1) I

-

-

-

Bacterial strains

Erythromycin

Kanamycin

Norfloxacin

Streptomycin

Tetracycline

Alone

MIC/2.5

MIC/5

Alone

MIC/2.5

MIC/5

Alone

MIC/2.5

MIC/5

Alone

MIC/2.5

MIC/5

Alone

MIC/2.5

MIC/5

AG100Atet

64

32 (2) S

32 (2) S

-

128 (>2)S

256 (>1) S

128

128 (1) I

256 (0.5) I

<2

<2

<2

2

2 (1) I

2 (1) I

AG102

32

64 (0.5) I

64 (0.5) I

<2

<2

<2

<2

<2

<2

-

256 (>1)S

256 (>1)S

<2

<2

<2

CM64

-

64 (>4) S

256 (>1)S

4

4 (1) I

8 (0.5) I

4

<2 (>2)S

<2 (>2)S

32

8 (4) S

32 (1) I

nt

nt

nt

KP63

16

1 (16) S

8 (2) S

32

32 (1) I

64 (0.5) I

-

-

-

<4

<4

<4

<2

<2

<2

PA124

128

64 (2) S

128 (1) I

128

4 (32) S

16 (8) S

64

32 (2) S

64 (1) I

nt

nt

nt

8

2 (4) S

8 (1) I

  1. MIC/2.5: concentration of plant extract added equal to 204.8 μg/mL for AG100ATET. CM64. KP63. AG102 and to 409.6 μg/ml for PA124.
  2. MIC/5: concentration of plant extract added equal to 102. 4 μg/mL for AG100ATET CM64. KP63. AG102; and to 204.8 μg/ml for PA124.
  3. (): Folds decreasing of MIC. S: synergy. I: indifference. nt: not tested; (−): MIC > 256 μg/ml.