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Table 6 Minimal inhibitory concentration (MIC) of antibiotics in absence and presence extracts Dorstenia psilurus (μg/ml)

From: Antibacterial and antibiotic-potentiation activities of the methanol extract of some cameroonian spices against Gram-negative multi-drug resistant phenotypes

Bacterial strains Antibiotics and MIC in absence and presence ofDorstenia psilurus extract
Ampicillin Cefepime Chloramphenicol Ciprofloxacin Cloxacillin
Alone MIC/2.5 MIC/5 Alone MIC/2 MIC/5 Alone MIC/2.5 MIC/5 Alone MIC/2.5 MIC/5 Alone MIC/2.5 MIC/5
AG100Atet - - - - - - 256 128 (2) S 256 (1) I 256 64 (4) S 128 (2) S - - -
AG102 - - - 128 256 (0.5) I 256 (0.5) I 16 4 (4) S 4 (4) S <2 <2 <2 - - -
CM64 - 256 (>1)S - - 64 (>4) S 64 (>4) S nt nt nt nt nt nt - 256 (>1) S -
KP63 - 32 (>8) S - 256 64 (4) S 128 (2) S - 64 (>4) S 256 (>1) S 64 64 (1) I 64 (1) I - 64 (>4) S 256 (>1) S
PA124 128 64 (2) S 64 (2) S 128 128 (1) I 128 (1) I 32 16 (2) S 32 (1) I 16 16 (1) I 16 (1) I - - -
Bacterial strains Erythromycin Kanamycin Norfloxacin Streptomycin Tetracycline
Alone MIC/2.5 MIC/5 Alone MIC/2.5 MIC/5 Alone MIC/2.5 MIC/5 Alone MIC/2.5 MIC/5 Alone MIC/2.5 MIC/5
AG100Atet 64 32 (2) S 32 (2) S - 128 (>2)S 256 (>1) S 128 128 (1) I 256 (0.5) I <2 <2 <2 2 2 (1) I 2 (1) I
AG102 32 64 (0.5) I 64 (0.5) I <2 <2 <2 <2 <2 <2 - 256 (>1)S 256 (>1)S <2 <2 <2
CM64 - 64 (>4) S 256 (>1)S 4 4 (1) I 8 (0.5) I 4 <2 (>2)S <2 (>2)S 32 8 (4) S 32 (1) I nt nt nt
KP63 16 1 (16) S 8 (2) S 32 32 (1) I 64 (0.5) I - - - <4 <4 <4 <2 <2 <2
PA124 128 64 (2) S 128 (1) I 128 4 (32) S 16 (8) S 64 32 (2) S 64 (1) I nt nt nt 8 2 (4) S 8 (1) I
  1. MIC/2.5: concentration of plant extract added equal to 204.8 μg/mL for AG100ATET. CM64. KP63. AG102 and to 409.6 μg/ml for PA124.
  2. MIC/5: concentration of plant extract added equal to 102. 4 μg/mL for AG100ATET CM64. KP63. AG102; and to 204.8 μg/ml for PA124.
  3. (): Folds decreasing of MIC. S: synergy. I: indifference. nt: not tested; (−): MIC > 256 μg/ml.