Ā | H&E Node positive | PCR Node positive | Percent upstaged by PCR |
---|
No Distant Metastases | 6 / 9 | 8 / 9 | 22%* |
Distant Metastases | 11 / 12 | 12 / 12 | 8% |
Total | 17 / 21 | 20 / 21 | 14% |
- *Upstaging by TNM criteria.
- The 21 SI-NENs included 3 patients with localized disease, 6 with nodal metastasis according to H&E assessment, and 12 with distant metastases (one was lymph node negative). PCR upstaged 2 of the 3 node negative patients to node positive, and the patient with node negative but metastatic disease was also node positive on PCR. Thus 3 of 21 (14%) patients were upstaged to node positive disease, with 2 patients upstaged in TNM staging.