| |
H&E Node positive
|
PCR Node positive
|
Percent upstaged by PCR
|
|---|
|
No Distant Metastases
|
6 / 9
|
8 / 9
|
22%*
|
|
Distant Metastases
|
11 / 12
|
12 / 12
|
8%
|
|
Total
|
17 / 21
|
20 / 21
|
14%
|
- *Upstaging by TNM criteria.
- The 21 SI-NENs included 3 patients with localized disease, 6 with nodal metastasis according to H&E assessment, and 12 with distant metastases (one was lymph node negative). PCR upstaged 2 of the 3 node negative patients to node positive, and the patient with node negative but metastatic disease was also node positive on PCR. Thus 3 of 21 (14%) patients were upstaged to node positive disease, with 2 patients upstaged in TNM staging.
