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Table 3 Allelic positivities of single nucleotide polymorphisms (SNPs) in the TLR4 gene in Japanese subjects.

From: The association of Toll-like receptor 4 gene polymorphisms with the development of emphysema in Japanese subjects: a case control study

dbSNP* Location
Position
Allele Emphysema
(N = 106)
Controls
(N = 137)
O.R. P
    Allelic Positivity
n (%)
  
rs10759930 promoter
119,501,442
T
C
92 (86.8)
62 (58.5)
111 (81.0)
83 (60.6)
1.54
0.92
0.229
0.741
rs1927914 promoter
119,504,546
A
G
92 (86.8)
62 (58.5)
111 (81.0)
83 (60.6)
1.54
0.92
0.229
0.741
rs12377632 intron 2
119,512,551
C
T
92 (86.8)
61 (57.5)
111 (81.0)
82 (59.9)
1.54
0.91
0.229
0.717
rs2149356 intron 2
119,514,020
G
T
93 (87.7)
61 (57.5)
111 (81.0)
82 (59.9)
1.68
0.91
0.157
0.717
rs11536889 3'UTR
119,517,952
G
C
88 (83.0)
58 (54.7)
127 (92.7)
58 (42.3)
0.38
1.65
0.019
0.055
rs7037117 3'UTR
119,523,484
A
G
102 (96.2)
44 (41.6)
133 (97.1)
51 (37.2)
0.77
1.20
0.711
0.497
rs7045953 3'UTR
119,525,616
A
G
106 (100)
18 (17.0)
137 (100)
21 (15.3)
-
1.13
-
0.728
  1. Subjects included patients with emphysema and control smokers
  2. *SNP designations are from the NCBI SNP database [29]. N = number of subjects. n = number of present alleles
  3. P values were calculated with χ2 tests of 2 × 2 contingency table