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Table 3 Allelic positivities of single nucleotide polymorphisms (SNPs) in the TLR4 gene in Japanese subjects.

From: The association of Toll-like receptor 4 gene polymorphisms with the development of emphysema in Japanese subjects: a case control study

dbSNP* Location Position Allele Emphysema (N = 106) Controls (N = 137) O.R. P
    Allelic Positivity n (%)   
rs10759930 promoter 119,501,442 T C 92 (86.8) 62 (58.5) 111 (81.0) 83 (60.6) 1.54 0.92 0.229 0.741
rs1927914 promoter 119,504,546 A G 92 (86.8) 62 (58.5) 111 (81.0) 83 (60.6) 1.54 0.92 0.229 0.741
rs12377632 intron 2 119,512,551 C T 92 (86.8) 61 (57.5) 111 (81.0) 82 (59.9) 1.54 0.91 0.229 0.717
rs2149356 intron 2 119,514,020 G T 93 (87.7) 61 (57.5) 111 (81.0) 82 (59.9) 1.68 0.91 0.157 0.717
rs11536889 3'UTR 119,517,952 G C 88 (83.0) 58 (54.7) 127 (92.7) 58 (42.3) 0.38 1.65 0.019 0.055
rs7037117 3'UTR 119,523,484 A G 102 (96.2) 44 (41.6) 133 (97.1) 51 (37.2) 0.77 1.20 0.711 0.497
rs7045953 3'UTR 119,525,616 A G 106 (100) 18 (17.0) 137 (100) 21 (15.3) - 1.13 - 0.728
  1. Subjects included patients with emphysema and control smokers
  2. *SNP designations are from the NCBI SNP database [29]. N = number of subjects. n = number of present alleles
  3. P values were calculated with χ2 tests of 2 × 2 contingency table