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Table 4 Allelic frequency and genotypic distribution of the rs11536889 in the TLR4 gene in emphysema and control groups

From: The association of Toll-like receptor 4 gene polymorphisms with the development of emphysema in Japanese subjects: a case control study

rs11536889 Type Emphysema
(N = 106)
Controls
(N = 137)
O.R. P P a
Allelic frequency, n (%) G 136(64.2) 206 (75.2) 0.59 0.0083  
  C 76 (35.8) 68 (24.8) 1.69*   
Genotypic distribution, n (%) GG 48 (45.3) 79 (57.7) 0.61 0.055  
  GC 40 (37.7) 48 (35.0) 1.12 0.664 0.034
  CC 18 (17.0) 10 (7.3) 2.60 0.019  
  1. N number of subjects. n number of present alleles or genotypes correspondingly
  2. P and Pa values were calculated with χ2 tests of 2 × 2 and 3 × 2 contingency tables, respectively
  3. *Odds Ratio = 1.69, 95% Confidence Intervals = 1.14-2.50
  4. Odds Ratio = 2.60, 95% Confidence Intervals = 1.17-5.78