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Table 1 The status of genomic and cell proliferation markers in the ICH-based subtypes

From: Luminal A and luminal B (HER2 negative) subtypes of breast cancer consist of a mixture of tumors with different genotype

Markers LumWalA Luminal B, HER2- Luminal B, HER2+ HER2 Basal-hke Total
No. of tumors 111 (30.6%) 95 (26.2%) 69 (19.0%) 41 (11.3%) 47 (12.9%) 363
Age (range) 58.6 (34–84) 54.8 (27–84) 54.7 (30–78) 58,9 (38–87) 56.8 (31–84) 56.7
Ki-67c14% 111 (100%) 0 (0%) 10 (14.5%) 1 (24.3%) 4 (8.5%) 126 (34.7%)
K6714% 0 (0%) 95 (100%) 59 (85.5%) 40 (97.8%) 43 (91.5%) 237 (65.3%)
DiploEd 78 (70.3%) 44 (46.3%) 11 (15.9%) 3 (7.3%) 8 (17.0%) 140 (38.6%)
Aneuploid 33 (29.7%) 51 (53.7%) 58 (84.1%) 38 (92.7%) 39 (83.0%) 223 (61.4%)
CIN- 74 (66.7%) 43 (45.3%) 10 (14.5%) 3 (7.3%) 10 (21.3%) 140 (38.6%)
CIN. 37 (33.3%) 52 (54.7%) 59 (85.5%) 38 (92.7%) 37 (787%) 223 (61.4%)
DipIod!ClN- 72 (64.9) 39 (41.1%) 8 (11.6%) 2 (4.9%) 8 (17.0%) 129 (35.5%)
AneuplodiClN+ 31 (27.9%) 47 (49.5%) 56 (81.2%) 372 (90.2%) 36 (76.6%) 207 (57.0%)
Grade 1 53 (47.7%) 15 (15.8%) 6 (8.7%) 0 (0%) 4 (8.5%) 78 (20.4%)
Grade 2 32 (28.8%) 23 (24.2%) 10 (14.5%) 2 (4.9%) 2 (4.3%) 69 (19.0%)
Grade 3 20 (18.0%) 56 (58.9%) 52 (58.9%) 38 (92.7%) 40 (85.1%) 206 (57.3%)
nd 6 1 1 1 1 10
  1. The numbers in the table indicate the number of tumors fitting each item. The numbers in parenthesis are the percentages of tumors fitting each hem. Ki-67+; tumors with a high Ki-67 index, Ki-67-; tumors with a ow Ki-67 index, CIN-; the absence of chromosomal instability, CIN+; the presence of chromosomal instability, Dip/CIN-IKi-67+; tumors with diploidiClN -IKi-67- features, Aneup/CIN÷/Ki-67÷; tumors.