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Table 3 Changes in pulmonary function in 35 patients undergoing surgery for ovarian cancer.

From: Influence of perioperative oxygen fraction on pulmonary function after abdominal surgery: a randomized controlled trial

  Change in PaO2/FiO2at the end of anesthesia (kPa) Change in FRC 2 h after extubation (mL)
  FiO2 = 0.30 FiO2 = 0.80 P value FiO2 = 0.30 FiO2 = 0.80 P value
  (n = 15) (n = 20)   (n = 8) (N = 12)  
Intention-to-treat −7.5 ± 10 -1.2 ± 10 0.10 -49 ± 507 −152 ± 382 0.70
  n = 13 n = 20   n = 7 n = 12  
Per-protocol * −7.1 ± 9 -1.2 ± 10 0.10 60 ± 435 −152 ± 382 0.35
  1. The data are mean difference form baseline ± SD. P values are calculated by Mann–Whitney test to compare the changes from baseline values between the two groups. PaO2 = arterial oxygen tension; FiO2 = inspired oxygen fraction; PaO2/FiO2 = oxygenation index; FRC = functional residual capacitity.
  2. * Excluded patients are described in Figure 1.