Influence of perioperative oxygen fraction on pulmonary function after abdominal surgery: a randomized controlled trial

Table 3 Changes in pulmonary function in 35 patients undergoing surgery for ovarian cancer.

	Change in PaO₂/FiO₂at the end of anesthesia (kPa)			Change in FRC 2 h after extubation (mL)
	FiO₂ = 0.30	FiO₂ = 0.80	P value	FiO₂ = 0.30	FiO₂ = 0.80	P value
	(n = 15)	(n = 20)		(n = 8)	(N = 12)
Intention-to-treat	−7.5 ± 10	-1.2 ± 10	0.10	-49 ± 507	−152 ± 382	0.70
	n = 13	n = 20		n = 7	n = 12
Per-protocol *	−7.1 ± 9	-1.2 ± 10	0.10	60 ± 435	−152 ± 382	0.35

The data are mean difference form baseline ± SD. P values are calculated by Mann–Whitney test to compare the changes from baseline values between the two groups. PaO₂ = arterial oxygen tension; FiO₂ = inspired oxygen fraction; PaO₂/FiO₂ = oxygenation index; FRC = functional residual capacitity.
* Excluded patients are described in Figure 1.

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