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Figure 5 | BMC Research Notes

Figure 5

From: Gremlin in the pathogenesis of hepatocellular carcinoma complicating chronic hepatitis C: an immunohistochemical and PCR study of human liver biopsies

Figure 5

Gel electrophoreograms of BMP expression among study groups. (a) BMP-7 mRNA expression in liver tissue from patients with chronic hepatitis C. BMP-7 expression is observed in lanes 1, 3, 4 and 5 at 163 bp, whereas no DNA bands are present in lane 2. Note the extra higher band at 250 bp. Lane 6 is a 25 bp size marker. (b): BMP-7 mRNA expression in cirrhotic liver tissue. PCR products are observed at 163 bp in lanes 1, 2, 3, 4 and 6. Lane 5 shows no PCR products. Lane 7 is a 25 bp size marker. (c): BMP-7 mRNA expression in cirrhotic liver tissue. PCR products are observed in lanes 8, 9 and 10, but not in lane 11. Lane 7 contains the marker. (d): BMP-7 mRNA expression in HCC cases. PCR products are observed in lanes 1, 7, 8, 9 and 10. No PCR products are observed in lanes 2, 3, 4 and 6. Lane 5 contains the marker. (Capillary electrophoresis using e-gene, HAD-GT12). (i) Bar graph showing the numbers of cases expressing BMP-7 mRNA among study groups. (ii) Correlations between BMP-7 mRNA expression and ductular reactions in the cirrhosis group.

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