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Table 6 Correlations between gremlin mRNA expression and studied markers in hepatitis and cirrhosis groups

From: Gremlin in the pathogenesis of hepatocellular carcinoma complicating chronic hepatitis C: an immunohistochemical and PCR study of human liver biopsies

Gremlin Grade Stage Ductular reaction CK 19 BMP 7
HCV r 0.136 0.699 * 0.276 0.223 0.051
p 0.615 0.003 0.301 0.04 0.851
Cirrhosis      
r 0.526   0.994   0.602
p 0.044 NP 0.001 NP 0.023
  1. Rho (r) Spearman coefficient * Statistically significant at p ≤ 0.05.
  2. NP Not performed because gremlin was expressed in 100% of cases and all 35 cases of this group received a score of 3 for CK19 positivity. Therefore, a correlation was not feasible.
  3. Note: a correlation was not performed with the stage (fixed stage 6 by definition).