Gremlin in the pathogenesis of hepatocellular carcinoma complicating chronic hepatitis C: an immunohistochemical and PCR study of human liver biopsies

Table 6 Correlations between gremlin mRNA expression and studied markers in hepatitis and cirrhosis groups

Gremlin	Grade	Stage	Ductular reaction	CK 19	BMP 7
HCV r	0.136	0.699 ^*	0.276	0.223	0.051
p	0.615	0.003	0.301	0.04	0.851
Cirrhosis
r	0.526		0.994		0.602
p	0.044	NP	0.001	NP	0.023

Rho (r) Spearman coefficient * Statistically significant at p ≤ 0.05.
NP Not performed because gremlin was expressed in 100% of cases and all 35 cases of this group received a score of 3 for CK19 positivity. Therefore, a correlation was not feasible.
Note: a correlation was not performed with the stage (fixed stage 6 by definition).

ISSN: 1756-0500