Critical COPD respiratory illness is linked to increased transcriptomic activity of neutrophil proteases genes

BMC Research Notes

Table 3 Gene expression levels by biological function of genes relatively up-regulated in the ICU group, based upon IPA results

Severe acute respiratory syndrome & Infection of respiratory tract
IPA p-Value 5,66E-19 and 7,46E-18 respectively
GeneSymbol	Corrected p-value	FCAbsolute
LCN2	0,004	10,37
LTF	0,004	9,86
BPI	0,012	7,20
HP	0,015	6,71
CEACAM8	0,027	4,80
PGLYRP1	0,016	4,54
CEBPE	0,009	4,49
TCN1	0,017	3,86
RNASE2	0,007	3,69
DEFA3	0,024	3,68
CD24	0,029	3,54
S100A12	0,031	3,40
HIST1H2AC	0,011	3,04
HIST1H1C	0,010	2,90
APCS	0,046	2,88
RAB13	0,019	2,63
STXBP2	0,034	2,55
GAPDH	0,039	2,52
TIMP1	0,009	2,33
PDXK	0,015	2,26
TUBB2C	0,010	2,16

ISSN: 1756-0500