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Table 4 Gene expression levels by biological function of genes relatively up-regulated in the ICU group, based upon IPA results

From: Critical COPD respiratory illness is linked to increased transcriptomic activity of neutrophil proteases genes

Inflammatory response
IPA p-Value: 5,70E-07
GeneSymbol Corrected p-value FCAbsolute
LCN2 0,004 10,37
LTF 0,004 9,86
ELANE 0,026 8,19
BPI 0,018 7,06
INHBA 0,007 7,12
HP 0,015 6,71
PRTN3 0,030 6,33
AZU1 0,038 6,13
CTSG 0,034 5,71
MPO 0,024 4,97
CEBPE 0,009 4,49
APP 0,004 4,06
RNASE2 0,007 3,69
DEFA3 0,024 3,68
MPP1 0,025 3,61
RAP1GAP 0,034 3,46
FCAR 0,024 2,98
APCS 0,046 2,88
MEFV 0,020 2,83
GNAO1 0,032 2,67
ELN 0,037 2,63
MGLL 0,023 2,61
VEGFA 0,019 2,60
GRK6 0,014 2,39
MAP2K3 0,045 2,37
POMC 0,038 2,25
CYBA 0,011 2,16
PRDX5 0,010 2,11
MUC1 0,030 2,06
UNC13D 0,014 2,02
SBDS 0,033 2,01
  1. FC: fold change of gene expression values in the ICU / non ICU group.